Publications

Authors:Smolen JS, Gladman D, McNeil HP, Mease PJ, Sieper J, Hojnik M, Nurwakagari P, Weinman J

Title:Predicting adherence to therapy in rheumatoid arthritis, psoriatic arthritis or ankylosing spondylitis: a large cross-sectional study

Journal:RMD Open Year:2019; Volume:5Issue:(1):Pages:e000585.

Authors:Winthrop KL, Weinblatt ME, Crow MK, Burmester GR, Mease PJ, So AK, Bykerk V, Van Vollenhoven RF, Dougados M, Kay J, Mariette X, Sieper J, Melchers F, Cronstein BN, Shevach E, Breedfeld FC, Kalden J, Smolen JS, Furst DE

Title:Unmet need in rheumatology: reports from the Targeted Therapies meeting 2018

Journal:Ann Rheum Dis Year:2019; :Pages:doi: 10.1136/annrheumdis-2018-214280. [Epub ahead of print].

Authors:Greese J, Diekhoff T, Sieper J, Schwenke C, Makowski MR, Poddubnyy D, Hamm B, Hermann KGA

Title:Detection of Sacroiliitis by Short-tau Inversion Recovery and T2-weighted Turbo Spin Echo Sequences: Results from the SIMACT Study

Journal:J Rheumatol Year:2019; :Pages:doi: 10.3899/jrheum.171425. [Epub ahead of print].

Authors:Rios Rodriguez V, Hermann KG, Weiß A, Listing J, Haibel H, Althoff C, Proft F, Behmer O, Sieper J, Poddubnyy D

Title:Progression of the structural damage in the sacroiliac joints in patients with early axial spondyloarthritis during a long-term anti-TNF treatment: six-year results of the ESTHER trial

Journal:Arthritis Rheumatol Year:2019; :Pages:doi: 10.1002/art.40786. [Epub ahead of print].

Authors:Poddubnyy D, Callhoff J, Spiller I, Listing J, Braun J, Sieper J, Rudwaleit M

Title:Diagnostic accuracy of inflammatory back pain for axial spondyloarthritis in rheumatological care

Journal:RMD Open Year:2018; Volume:4Issue:(2):Pages:e000825.

Authors:Braun J, Baraliakos X, Deodhar A, Poddubnyy D, Emery P, Delicha EM, Talloczy Z, Porter B

Title:Secukinumab shows sustained efficacy and low structural progression in ankylosing spondylitis: 4-year results from the MEASURE 1 study

Journal:Rheumatology (Oxford) Year:2018; :Pages:doi: 10.1093/rheumatology/key375. [Epub ahead of print].

Authors:Ulas ST, Diekhoff T, Hermann KGA, Poddubnyy D, Hamm B, Makowski MR

Title:Susceptibility-weighted MR imaging to improve the specificity of erosion detection: a prospective feasibility study in hand arthritis

Journal:Skeletal Radiol Year:2018; :Pages:doi: 10.1007/s00256-018-3116-0. [Epub ahead of print].

Authors:Braun J, Deodhar A, Landewé R, Baraliakos X, Miceli-Richard C, Sieper J, Quebe-Fehling E, Martin R, Porter B, Gandhi KK, van der Heijde D; MEASURE 1 and MEASURE 2 study groups

Title:Impact of baseline C-reactive protein levels on the response to secukinumab in ankylosing spondylitis: 3-year pooled data from two phase III studies

Journal:RMD Open Year:2018; Volume:4Issue:(2):Pages:e000749.

Authors:Riechers E, Baerlecken N, Baraliakos X, Achilles-Mehr Bakhsh K, Aries P, Bannert B, Becker K, Brandt-Jürgens J, Braun J, Ehrenstein B, Euler HH, Fleck M, Hein R, Karberg K, Köhler L, Matthias T, Max R, Melzer A, Meyer-Olson D, Rech J, Rockwitz K, Rudwaleit M, Schmidt RE, Schweikhard E, Sieper J, Stille C, von Hinüber U, Wagener P, Weidemann HF, Zinke S, Witte T

Title:Sensitivity and specifity of autoantibodies against CD74 in axial spondyloarthritis

Journal:Arthritis Rheumatol Year:2018; :Pages:doi: 10.1002/art.40777. [Epub ahead of print].

Authors:van der Heijde D, Cheng-Chung Wei J, Dougados M, Mease P, Deodhar A, Maksymowych WP, Van den Bosch F, Sieper J, Tomita T, Landewé R, Zhao F, Krishnan E, Adams DH, Pangallo B, Carlier H; COAST-V study group

Title:Ixekizumab, an interleukin-17A antagonist in the treatment of ankylosing spondylitis or radiographic axial spondyloarthritis in patients previously untreated with biological disease-modifying anti-rheumatic drugs (COAST-V): 16 week results of a phase 3 randomised, double-blind, active-controlled and placebo-controlled trial

Journal:Lancet Year:2018; Volume:392Issue:(10163):Pages:2441-2451.

Authors:Deodhar A, Poddubnyy D, Pacheco-Tena C, Salvarani C, Lespessailles E, Rahman P, Järvinen P, Sanchez-Burson J, Gaffney K, Lee EB, Krishnan E, Santisteban S, Li X, Zhao F, Carlier H, Reveille JD; COAST-W study group

Title:Efficacy and Safety of Ixekizumab in the Treatment of Radiographic Axial Spondyloarthritis: 16 Week Results of a Phase 3 Randomized, Double-Blind, Placebo Controlled Trial in Patients with Prior Inadequate Response or Intolerance to Tumor Necrosis Factor Inhibitors

Journal:Arthritis Rheumatol Year:2018; :Pages:doi: 10.1002/art.40753. [Epub ahead of print].

Authors:Diekhoff T, Ulas ST, Poddubnyy D, Schneider U, Hermann S, Biesen R, Burmester GR, Hamm B, Hermann KG

Title:Ultra-low-dose CT detects synovitis in patients with suspected rheumatoid arthritis

Journal:Ann Rheum Dis Year:2019; Volume:78Issue:(1):Pages:31-35.

Authors:Deodhar A, Gensler LS, Sieper J, Clark M, Calderon C, Wang Y, Zhou Y, Leu JH, Campbell K, Sweet K, Harrison DD, Hsia EC, van der Heijde D

Title:Three Multicenter, Randomized, Double-Blind, Placebo-Controlled Studies Evaluating the Efficacy and Safety of Ustekinumab in Axial Spondyloarthritis

Journal:Arthritis Rheumatol Year:2019; Volume:71Issue:(2):Pages:258-270.

Authors:Schulte-Wrede U, Sörensen T, Grün JR, Häupl T, Hirseland H, Steinbrich-Zöllner M, Wu P, Radbruch A, Poddubnyy D, Sieper J, Syrbe U, Grützkau A

Title:An explorative study on deep profiling of peripheral leukocytes to identify predictors for responsiveness to anti-tumour necrosis factor alpha therapies in ankylosing spondylitis: natural killer cells in focus

Journal:Arthritis Res Ther Year:2018; Volume:20Issue:(1):Pages:191.

Authors:Diekhoff T, Greese J, Sieper J, Poddubnyy D, Hamm B, Hermann KA

Title:Improved detection of erosions in the sacroiliac joints on MRI with volumetric interpolated breath-hold examination (VIBE): results from the SIMACT study

Journal:Ann Rheum Dis Year:2018; Volume:77Issue:(11):Pages:1585-1589.

Authors:van Lunteren M, Sepriano A, Landewé R, Sieper J, Rudwaleit M, van der Heijde D, van Gaalen F

Title:Do ethnicity, degree of family relationship, and the spondyloarthritis subtype in affected relatives influence the association between a positive family history for spondyloarthritis and HLA-B27 carriership? Results from the worldwide ASAS cohort

Journal:Arthritis Res Ther Year:2018; Volume:20Issue:(1):Pages:166.

Authors:Landewé R, Sieper J, Mease P, Inman RD, Lambert RG, Deodhar A, Marzo-Ortega H, Magrey M, Kiltz U, Wang X, Li M, Zhong S, Mostafa NM, Lertratanakul A, Pangan AL, Anderson JK

Title:Efficacy and safety of continuing versus withdrawing adalimumab therapy in maintaining remission in patients with non-radiographic axial spondyloarthritis (ABILITY-3): a multicentre, randomised, double-blind study

Journal:Lancet Year:2018; Volume:392Issue:(10142):Pages:134-144.

Authors:Baeten D, Østergaard M, Wei JC, Sieper J, Järvinen P, Tam LS, Salvarani C, Kim TH, Solinger A, Datsenko Y, Pamulapati C, Visvanathan S, Hall DB, Aslanyan S, Scholl P, Padula SJ

Title:Risankizumab, an IL-23 inhibitor, for ankylosing spondylitis: results of a randomised, double-blind, placebo-controlled, proof-of-concept, dose-finding phase 2 study

Journal:Ann Rheum Dis Year:2018; Volume:77Issue:(9):Pages:1295-1302.

Authors:Proft F, Poddubnyy D

Title:Ankylosing spondylitis and axial spondyloarthritis: recent insights and impact of new classification criteria

Journal:Ther Adv Musculoskelet Dis Year:2018; Volume:10Issue:(5-6):Pages:129-139.

Authors:Redeker I, Hoffmann F, Callhoff J, Haibel H, Sieper J, Zink A, Poddubnyy D

Title:Response to 'A missing pebble in the mosaic of rheumatic diseases and mental health: younger does not always mean happier' by Alunno et al.

Journal:Ann Rheum Dis Year:2018; :Pages:doi: 10.1136/annrheumdis-2018-213620. [Epub ahead of print].

Authors:Protopopov M, Poddubnyy D

Title:Radiographic progression in non-radiographic axial spondyloarthritis

Journal:Expert Rev Clin Immunol Year:2018; Volume:14Issue:(6):Pages:525-533.

Authors:Syrbe U, Baraliakos X

Title:Spondylarthritiden

Journal:Z Rheumatol Year:2018; :Pages:doi: 10.1007/s00393-018-0475-9.

Authors:Häupl T, Skapenko A, Hoppe B, Skriner K, Burkhardt H, Poddubnyy D, Ohrndorf S, Sewerin P, Mansmann U, Stuhlmüller B, Schulze-Koops H, Burmester GR

Title:Biomarker und Bildgebung zur Diagnose und Stratifizierung der rheumatoiden Arthritis und Spondylarthritis im BMBF-Verbund ArthroMark

Journal:Z Rheumatol Year:2018; Volume:77Issue:(Suppl. 1):Pages:16-22.

Authors:Ziegeler K, Eshkal H, Schorr C, Sieper J, Diekhoff T, Makowski MR, Hamm B, Hermann KG

Title:Age- and Sex-dependent Frequency of Fat Metaplasia and Other Structural Changes of the Sacroiliac Joints in Patients without Axial Spondyloarthritis: A Retrospective, Cross-sectional MRI Study

Journal:J Rheumatol Year:2018; Volume:45Issue:(7):Pages:915-921.

Authors:Schaible HG, Chang HD, Grässel S, Haibel H, Hess A, Kamradt T, Radbruch A, Schett G, Stein C, Straub RH.

Title:Forschungsverbund Neuroimmunologie und Schmerz (Neuroimpa) im Forschungsnetz Muskuloskelettale Erkrankungen

Journal:Z Rheumatol Year:2018; Volume:77Issue:(Suppl 1):Pages:24-30.

Authors:Becker J, Berger F, Schindlbeck KA, Poddubnyy D, Koch PM, Preiß JC, Siegmund B, Marzinzik F, Maul J

Title:Restless legs syndrome is a relevant comorbidity in patients with inflammatory bowel disease

Journal:Int J Colorectal Dis Year:2018; Volume:33Issue:(7):Pages:955-962.

Authors:van der Heijde D, Sieper J, Maksymowych WP, Lambert RG, Chen S, Hojnik M, Anderson JK, Pangan AL

Title:Clinical and MRI remission in patients with nonradiographic axial spondyloarthritis who received long-term open-label adalimumab treatment: 3-year results of the ABILITY-1 trial

Journal:Arthritis Res Ther Year:2018; Volume:20Issue:(1):Pages:61.

Authors:Buchbinder R, van Tulder M, Öberg B, Costa LM, Woolf A, Schoene M, Croft P; Lancet Low Back Pain Series Working Group

Title:Low back pain: a call for action

Journal:Lancet Year:2018; Volume:391Issue:(10137):Pages:2384-2388.

Authors:Hartvigsen J, Hancock MJ, Kongsted A, Louw Q, Ferreira ML, Genevay S, Hoy D, Karppinen J, Pransky G, Sieper J, Smeets RJ, Underwood M; Lancet Low Back Pain Series Working Group

Title:What low back pain is and why we need to pay attention

Journal:Lancet Year:2018; Volume:391Issue:(10137):Pages:2356-2367.

Authors:Schwedler C, Häupl T, Kalus U, Blanchard V, Burmester GR, Poddubnyy D, Hoppe B

Title:Hypogalactosylation of immunoglobulin G in rheumatoid arthritis: relationship to HLA-DRB1 shared epitope, anticitrullinated protein antibodies, rheumatoid factor, and correlation with inflammatory activity

Journal:Arthritis Res Ther Year:2018; Volume:20Issue:(1):Pages:44.

Authors:Van den Bosch F, Mease PJ, Sieper J, Baeten DL, Xia Y, Chen S, Pangan AL, Song IH

Title:Long-term efficacy and predictors of remission following adalimumab treatment in peripheral spondyloarthritis: 3-year results from ABILITY-2

Journal:RMD Open Year:2018; Volume:4Issue:(1):Pages:e000566.

Authors:Redeker I, Hoffmann F, Callhoff J, Haibel H, Sieper J, Zink A, Poddubnyy D

Title:Determinants of psychological well-being in axial spondyloarthritis: an analysis based on linked claims and patient-reported survey data

Journal:Ann Rheum Dis Year:2018; Volume:77Issue:(7):Pages:1017-1024.

Authors:Rademacher J, Poddubnyy D

Title:Emerging drugs for the treatment of axial spondyloarthritis

Journal:Expert Opin Emerg Drugs Year:2018; Volume:23Issue:(1):Pages:83-96.

Authors:Dubreuil M, Sieper J

Title:Editorial: Inflammatory Back Pain and Axial Spondyloarthritis: Lessons for Clinical Practice and Epidemiologic Research

Journal:Arthritis Rheumatol Year:2018; Volume:70Issue:(7):Pages:981-983.

Authors:Hebeisen M, Neuenschwander R, Scherer A, Exer P, Weber U, Tamborrini G, Micheroli R, Wildi LM, Zufferey P, Nissen MJ, Villiger PM, Bernhard J, Finckh A, van der Horst-Bruinsma IE, Sieper J, Landewé R, van der Heijde D, Ciurea A; rheumatologists of the Swiss Clinical Quality Management Program

Title:Response to Tumor Necrosis Factor Inhibition in Male and Female Patients with Ankylosing Spondylitis: Data from a Swiss Cohort.

Journal:J Rheumatol Year:2018; Volume:45Issue:(4):Pages:506-512.

Authors:Baraliakos X, Berenbaum F, Favalli EG, Olivieri I, Ostendorf B, Poddubnyy D, DE Vlam K

Title:Challenges and Advances in Targeting Remission in Axial Spondyloarthritis

Journal:J Rheumatol Year:2018; Volume:45Issue:(2):Pages:153-157.

Authors:Poddubnyy D, Listing J, Haibel H, Knüppel S, Rudwaleit M, Sieper J

Title:Functional relevance of radiographic spinal progression in axial spondyloarthritis: results from the GErman SPondyloarthritis Inception Cohort

Journal:Rheumatology (Oxford) Year:2018; Volume:57Issue:(4):Pages:703-711.

Authors:Marzo-Ortega H, Sieper J, Kivitz A, Blanco R, Cohen M, Delicha EM, Rohrer S, Richards H

Title:Secukinumab provides sustained improvements in the signs and symptoms of active ankylosing spondylitis with high retention rate: 3-year results from the phase III trial, MEASURE 2

Journal:RMD Open Year:2017; Volume:3Issue:(2):Pages:e000592.

Authors:Rios Rodriguez V, Llop M, Poddubnyy D.

Title:Hematopoietic and mesenchymal stem cells: a promising new therapy for spondyloarthritis?

Journal:Immunotherapy Year:2017; Volume:9Issue:(11):Pages:899-911.

Authors:Wendling D, Prati C, Sieper J

Title:Disease activity in ankylosing spondylitis: the global therapeutic target

Journal:Ann Rheum Dis Year:2018; Volume:77Issue:(8):Pages:1095-1096.

Authors:Protopopov M, Sieper J, Haibel H, Listing J, Rudwaleit M, Poddubnyy D

Title:Relevance of structural damage in the sacroiliac joints for the functional status and spinal mobility in patients with axial spondyloarthritis: results from the German Spondyloarthritis Inception Cohort.

Journal:Arthritis Res Ther Year:2017; Volume:19Issue:(1):Pages:240.

Authors:Poddubnyy D, Sieper J.

Title:What is the best treatment target in axial spondyloarthritis: tumour necrosis factor α, interleukin 17, or both?

Journal:Rheumatology (Oxford) Year:2017; :Pages:doi: 10.1093/rheumatology/kex361. [Epub ahead of print].

Authors:Rademacher J, Haibel H, Poddubnyy D, Ignatius R, Schneider T.

Title:Chronic meningococcaemia-a medical oxymoron

Journal:Rheumatology (Oxford) Year:2017; Volume:56Issue:(10):Pages:1819-1821.

Authors:Rios Rodriguez V, Poddubnyy D.

Title:Tumor necrosis factor-α (TNFα) inhibitors in the treatment of nonradiographic axial spondyloarthritis: current evidence and place in therapy

Journal:Ther Adv Musculoskelet Dis. Year:2017; Volume:9Issue:(8):Pages:197-210.

Authors:Winthrop KL, Strand V, van der Heijde D, Mease P, Crow M, Weinblatt M, Bathon J, Burmester GR, Dougados M, Kay J, Mariette X, Van Vollenhoven R, Sieper J, Melchers F, Breedfeld FC, Kalden J, Smolen JS, Furst DE.

Title:The unmet need in rheumatology: Reports from the targeted therapies meeting 2017.

Journal:Clin Immunol. Year:2017; Volume:186:Pages:87-93.

Authors:Poddubnyy D, Sieper J.

Title:Mechanism of New Bone Formation in Axial Spondyloarthritis.

Journal:Curr Rheumatol Rep. Year:2017; Volume:19Issue:(9):Pages:55.

Authors:Smolen JS, Schöls M, Braun J, Dougados M, FitzGerald O, Gladman DD, Kavanaugh A, Landewé R, Mease P, Sieper J, Stamm T, Wit M, Aletaha D, Baraliakos X, Betteridge N, Bosch FVD, Coates LC, Emery P, Gensler LS, Gossec L, Helliwell P, Jongkees M, Kvien TK, Inman RD, McInnes IB, Maccarone M, Machado PM, Molto A, Ogdie A, Poddubnyy D, Ritchlin C, Rudwaleit M, Tanew A, Thio B, Veale D, Vlam K, Heijde DV.

Title:Treating axial spondyloarthritis and peripheral spondyloarthritis, especially psoriatic arthritis, to target: 2017 update of recommendations by an international task force.

Journal:Ann Rheum Dis Year:2018; Volume:77Issue:(1):Pages:3-17.

Authors:Bukowska A, Spiller L, Wolke C, Lendeckel U, Weinert S, Hoffmann J, Bornfleth P, Kutschka I, Gardemann A, Isermann B, Goette A

Title:Protective regulation of the ACE2/ACE gene expression by estrogen in human atrial tissue from elderly men

Journal:Exp Biol Med (Maywood) Year:2017; Volume:242Issue:(14):Pages:1412-1423.

Authors:Hartl A, Sieper J, Syrbe U, Listing J, Hermann KG, Rudwaleit M, Poddubnyy D.

Title:Serum levels of leptin and high molecular weight adiponectin are inversely associated with radiographic spinal progression in patients with ankylosing spondylitis: results from the ENRADAS trial

Journal:Arthritis Res Ther. Year:2017; Volume:19Issue:(1):Pages:140.

Authors:Proft F, Muche B, Listing J, Rios-Rodriguez V, Sieper J, Poddubnyy D.

Title:Study protocol: COmparison of the effect of treatment with Nonsteroidal anti-inflammatory drugs added to anti-tumour necrosis factor a therapy versus anti-tumour necrosis factor a therapy alone on progression of StrUctural damage in the spine over two...

Journal:BMJ Open. Year:2017; Volume:7Issue:(6):Pages:e014591.

Authors:Proft F, Schulze-Koops H, Grunke M, Schrezenmeier E, Halleck F, Henes J, Unger L, Schmidt E, Fiehn C, Jacobi A, Iking-Konert C, Kneitz C, Schmidt RE, Bannert B, Voll RE, Fischer-Betz R, Kötter I, Tony HP, Holle J, Aringer M, Erler A, Behrens F, Burmester GR, Dörner T.

Title:Sicherheit und Wirksamkeitshinweise zum Off-label-Einsatz von Biologikatherapien nach Versagen konventioneller Therapien bei Patienten mit entzündlich rheumatischen Erkrankungen

Journal:Z Rheumatol. Year:2018; Volume:77Issue:(1):Pages:28-39.

Authors:Proft F, Fleck M, Fiehn C, Schulze-Koops H, Witt M, Dörner T, Henes JC.

Title:Wirksamkeits- und Sicherheitsanalyse von Off-label-Biologikatherapien bei Patienten mit autoinflammatorischen Erkrankungen

Journal:Z Rheumatol. Year:2018; Volume:77Issue:(1):Pages:46-54.

Authors:Wei JC, Baeten D, Sieper J, Deodhar A, Bhosekar V, Martin R, Porter B.

Title:Efficacy and safety of secukinumab in Asian patients with active ankylosing spondylitis: 52-week pooled results from two phase 3 studies

Journal:Int J Rheum Dis. Year:2017; Volume:20Issue:(5):Pages:589-596.

Authors:Szilagyi BA, Triebus J, Kressler C, de Almeida M, Tierling S, Durek P, Mardahl M, Szilagyi A, Floess S, Huehn J, Syrbe U, Walter J, Polansky JK, Hamann A.

Title:Rituximab zur Behandlung von Poly- und Dermatomyositis

Journal:Z Rheumatol. Year:2018; Volume:77Issue:(1):Pages:40-45.

Authors:Henes JC, Schulze-Koops H, Witt M, Tony HP, Mueller F, Grunke M, Czihal M, Dörner T, Proft F.

Title:Off-label-Biologikatherapie bei Patienten mit Großgefäßvaskulitiden und/oder Polymyalgia rheumatica

Journal:Z Rheumatol. Year:2018; Volume:77Issue:(1):Pages:12-20.

Authors:van der Heijde D, Dougados M, Landewé R, Sieper J, Maksymowych WP, Rudwaleit M, Van den Bosch F, Braun J, Mease PJ, Kivitz AJ, Walsh J, Davies O, Bauer L, Hoepken B, Peterson L, Deodhar A.

Title:Sustained efficacy, safety and patient-reported outcomes of certolizumab pegol in axial spondyloarthritis: 4-year outcomes from RAPID-axSpA

Journal:Rheumatology (Oxford). Year:2017; Volume:56Issue:(9):Pages:1498-1509.

Authors:Friedrich S, Lüders S, Werner SG, Glimm AM, Burmester GR, Riemekasten G, Backhaus M, Ohrndorf S.

Title:Disturbed microcirculation in the hands of patients with systemic sclerosis detected by fluorescence optical imaging: a pilot study.

Journal:Arthritis Res Ther. Year:2017; Volume:19Issue:(1):Pages:87.

Authors:Dougados M, van der Heijde D, Sieper J, Braun J, Citera G, Lenaerts J, van den Bosch F, Wei JC, Pedersen R, Bonin R, Jones H, Marshall L, Logeart I, Vlahos B, Bukowski JF, Maksymowych WP.

Title:Effects of Long-term Etanercept Treatment on Clinical Outcomes and Objective Signs of Inflammation in Early Non-Radiographic Axial Spondyloarthritis: 104-Week Results From the EMBARK Study.

Journal:Arthritis Care Res (Hoboken). Year:2017; Volume:69Issue:(10):Pages:1590-1598.

Authors:Weiß A, Minden K, Listing J, Foeldvari I, Sieper J, Rudwaleit M.

Title:Course of patients with juvenile spondyloarthritis during 4 years of observation, juvenile part of GESPIC.

Journal:RMD Open. Year:2017; Volume:3Issue:(1):Pages:e000366.

Authors:Baraliakos X, Sieper J, Chen S, Pangan AL, Anderson JK.

Title:Non-radiographic axial spondyloarthritis patients without initial evidence of inflammation may develop objective inflammation over time.

Journal:Rheumatology (Oxford) Year:2017; Volume:56Issue:(7):Pages:1162-1166.

Authors:Heftdal LD, Andersen T, Jæhger D, Woetmann A, Østgård R, Kenngott EE, Syrbe U, Sieper J, Hvid M, Deleuran B, Kragstrup TW.

Title:Synovial cell production of IL-26 induces bone mineralization in spondyloarthritis.

Journal:J Mol Med (Berl). Year:2017; Volume:95Issue:(7):Pages:779-787.

Authors:Lüders S, Friedrich S, Ohrndorf S, Glimm AM, Burmester GR, Riemekasten G, Backhaus M.

Title:Detection of severe digital vasculopathy in systemic sclerosis by colour Doppler sonography is associated with digital ulcers.

Journal:Rheumatology (Oxford). Year:2017; Volume:56Issue:(11):Pages:1865-1873.

Authors:Mease PJ, Van den Bosch F, Sieper J, Xia Y, Pangan AL, Song IH.

Title:Performance of 3 Enthesitis Indices in Patients with Peripheral Spondyloarthritis During Treatment with Adalimumab.

Journal:J Rheumatol. Year:2017; Volume:44Issue:(5):Pages:599-608.

Authors:Diekhoff T, Hermann KA, Greese J, Schwenke C, Poddubnyy D, Hamm B, Sieper J.

Title:Comparison of MRI with radiography for detecting structural lesions of the sacroiliac joint using CT as standard of reference: results from the SIMACT study

Journal:Ann Rheum Dis. Year:2017; Volume:76Issue:(9):Pages:1502-1508.

Authors:Marzo-Ortega H, Sieper J, Kivitz A, Blanco R, Cohen M, Martin R, Readie A, Richards HB, Porter B; MEASURE 2 STUDY GROUP.

Title:Secukinumab and Sustained Improvement in Signs and Symptoms of Patients With Active Ankylosing Spondylitis Through Two Years: Results From a Phase III Study.

Journal:Arthritis Care Res (Hoboken). Year:2017; Volume:69Issue:(7):Pages:1020-1029.

Authors:Szilagyi BA, Triebus J, Kressler C, de Almeida M, Tierling S, Durek P, Mardahl M, Szilagyi A, Floess S, Huehn J, Syrbe U, Walter J, Polansky JK, Hamann A.

Title:Gut memories do not fade: epigenetic regulation of lasting gut homing receptor expression in CD4+ memory T cells

Journal:Mucosal Immunol. Year:2017; Volume:10Issue:(6):Pages:1443-1454.

Authors:Sieper J, Poddubnyy D.

Title:Axial spondyloarthritis

Journal:Lancet Year:2017; Volume:390Issue:(10089):Pages:73-84.

Authors:van der Heijde D, Ramiro S, Landewé R, Baraliakos X, Van den Bosch F, Sepriano A, Regel A, Ciurea A, Dagfinrud H, Dougados M, van Gaalen F, Géher P, van der Horst-Bruinsma I, Inman RD, Jongkees M, Kiltz U, Kvien TK, Machado PM, Marzo-Ortega H, Molto A, Navarro-Compàn V, Ozgocmen S, Pimentel-Santos FM, Reveille J, Rudwaleit M, Sieper J, Sampaio-Barros P, Wiek D, Braun J.

Title:2016 update of the ASAS-EULAR management recommendations for axial spondyloarthritis

Journal:Ann Rheum Dis. Year:2017; Volume:76Issue:(6):Pages:978-991.

Authors:Poddubnyy D.

Title:Radiographic Evaluation of Sacroiliac Joints in Axial Spondyloarthritis - Still Worth Performing?

Journal:J Rheumatol. Year:2017; Volume:44Issue:(1):Pages:1-3.

Authors:Sieper J, Wood R, Kachroo S.

Title:Reply to the editorial: Can we currently and confidently assess the true burden of illness due to non-radiographic axial spondyloarthritis? by S. van der Linden and M.A. Khan.

Journal:Clin Exp Rheumatol. Year:2016; Volume:34Issue:(6):Pages:1121.

Authors:Braun J, Baraliakos X, Deodhar A, Baeten D, Sieper J, Emery P, Readie A, Martin R, Mpofu S, Richards HB; MEASURE 1 study group

Title:Effect of secukinumab on clinical and radiographic outcomes in ankylosing spondylitis: 2-year results from the randomised phase III MEASURE 1 study

Journal:Ann Rheum Dis. Year:2016; Volume:76Issue:(6):Pages:1070-1077.

Authors:Kiltz U, Rudwaleit M, Sieper J, Braun J.

Title:Evidenzbasierte Empfehlung zur Diagnostik und Therapie der axialen Spondyloarthritis

Journal:Z Rheumatol. Year:2016; Volume:76Issue:(2):Pages:111-117.

Authors:Braun J, Sieper J.

Title:Low progression rate to ankylosing spondylitis (AS) in patients with presumable non-radiographic axial spondyloarthritis (nr-axSpA)

Journal:Arthritis Rheumatol Year:2016; Volume:69Issue:(3):Pages:676-677.

Authors:Sieper J.

Title:New treatment targets for axial spondyloarthritis

Journal:J Immunol. Year:2016; Volume:55Issue:(Suppl.2):Pages:ii38-ii42.

Authors:Sieper J, Hu X, Black CM, Grootscholten K, van den Broek RW, Kachroo S.

Title:Systematic review of clinical, humanistic, and economic outcome comparisons between radiographic and non-radiographic axial spondyloarthritis

Journal:Semin Arthritis Rheum. Year:2016; Volume:46Issue:(6):Pages:746-753.

Authors:Durek P, Nordström K, Gasparoni G, Salhab A, Kressler C, de Almeida M, Bassler K, Ulas T, Schmidt F, Xiong J, Glažar P, Klironomos F, Sinha A, Kinkley S, Yang X, Arrigoni L, Amirabad AD, Ardakani FB, Feuerbach L, Gorka O, Ebert P, Müller F, Li N, Frischbutter S, Schlickeiser S, Cendon C, Fröhler S, Felder B, Gasparoni N, Imbusch CD, Hutter B, Zipprich G, Tauchmann Y, Reinke S, Wassilew G, Hoffmann U, Richter AS, Sieverling L; DEEP Consortium., Chang HD, Syrbe U, Kalus U, Eils J, Brors B, Manke T, Ruland J, Lengauer T, Rajewsky N, Chen W, Dong J, Sawitzki B, Chung HR, Rosenstiel P, Schulz MH, Schultze JL, Radbruch A, Walter J, Hamann A, Polansky JK.

Title:Epigenomic Profiling of Human CD4+ T Cells Supports a Linear Differentiation Model and Highlights Molecular Regulators of Memory Development

Journal:Immunity. Year:2016; Volume:45Issue:(5):Pages:1148-1161.

Authors:Poddubnyy D, Fedorova A, Listing J, Haibel H, Baraliakos X, Braun J, Sieper J.

Title:Physical Function and Spinal Mobility Remain Stable Despite Radiographic Spinal Progression in Patients with Ankylosing Spondylitis Treated with TNF-α Inhibitors for Up to 10 Years

Journal:J Rheumatol. Year:2016; Volume:43Issue:(12):Pages:2142-2148.

Authors:Thomas GP, Willner D, Robinson PC, Cortes A, Duan R, Rudwaleit M, Akkoc N, Braun J, Chou CT, Maksymowych WP, Ozgocmen S, Roussou E, Sieper J, Valle-Oñate R, van der Heijde D, Wei J, Leo P, Brown MA; and the International Genetics of Ankylosing Spondylitis Consortium.

Title:Genetic diagnostic profiling in axial spondyloarthritis: a real world study

Journal:Clin Exp Rheumatol. Year:2016; Volume:35Issue:(2):Pages:229-233.

Authors:Sieper J, Holbrook T, Black CM, Wood R, Hu X, Kachroo S.

Title:Burden of illness associated with non-radiographic axial spondyloarthritis: a multiperspective European cross-sectional observational study

Journal:Clin Exp Rheumatol. Year:2016; Volume:34Issue:(6):Pages:975-983.

Authors:Balazcs E, Sieper J, Bickham K, Mehta A, Frontera N, Stryszak P, Popmihajlov Z, Peloso PM.

Title:A randomized, clinical trial to assess the relative efficacy and tolerability of two doses of etoricoxib versus naproxen in patients with ankylosing spondylitis

Journal:BMC Musculoskelet Disord. Year:2016; Volume:13Issue:(1):Pages:426.

Authors:van der Heijde D, Deodhar A, Fleischmann R, Mease PJ, Rudwaleit M, Nurminen T, Davies BPharm O.

Title:Early Disease Activity or Clinical Response Predict Long-Term Outcomes with Certolizumab Pegol in Axial Spondyloarthritis or Psoriatic Arthritis

Journal:Arthritis Care Res (Hoboken). Year:2017; Volume:69Issue:(7):Pages:1030-1039.

Authors:Rudwaleit M, Landewé R, Sieper J.

Title:Ankylosing Spondylitis and Axial Spondyloarthritis

Journal:N Engl J Med. Year:2016; Volume:375Issue:(13):Pages:1302-1303.

Authors:Pink M, Ratsch BA, Mardahl M, Durek P, Polansky JK, Karl M, Baumgrass R, Wallner S, Cadenas C, Gianmoena K, Floess S, Chen W, Nordstroem K, Tierling S, Olek S, Walter J, Hamann A, Syrbe U.

Title:Imprinting of Skin/Inflammation Homing in CD4+ T Cells Is Controlled by DNA Methylation within the Fucosyltransferase 7 Gene

Journal:J Immunol. Year:2016; Volume:197Issue:(8):Pages:3406-3414.

Authors:Sieper J, Deodhar A, Marzo-Ortega H, Aelion JA, Blanco R, Jui-Cheng T, Andersson M, Porter B, Richards HB; MEASURE 2 Study Group.

Title:Secukinumab efficacy in anti-TNF-naive and anti-TNF-experienced subjects with active ankylosing spondylitis: results from the MEASURE 2 Study

Journal:Ann Rheum Dis. Year:2016; Volume:76Issue:(3):Pages:571-592.

Authors:Mardahl M, Schröter MF, Engelbert D, Pink M, Sperandio M, Hamann A, Syrbe U.

Title:Core 2 ß1,6-N-acetylglucosaminyltransferase-I, crucial for P-selectin ligand expression is controlled by a distal enhancer regulated by STAT4 and T-bet in CD4+ T helper cells 1

Journal:Mol Immunol. Year:2016; Issue:(77):Pages:132-140.

Authors:Baraliakos X, Heldmann F, van den Bosch F, Burmester G, Gaston H, van der Horst-Bruinsma IE, Krause A, Schmidt R, Schneider M, Sieper J, Andermann B, van Tubergen A, Witt M, Braun J.

Title:Long-term efficiency of infliximab in patients with ankylosing spondylitis: real life data confirm the potential for dose reduction

Journal:RMD Open Year:2016; Volume:2Issue:(2):Pages:e000272.

Authors:U. Kiltz, J. Sieper, M. Backhaus, B. Buss, E. Gromnica-Ihle, H. Haíbel, L. Hammel, K. Karberg, S. Rehart, M. Rudwaleit, F. Schuch, P. Steffens-Korbanka, J. Braun

Title:"Treat-to-target (T2T)" Empfehlungen für die Behandlung von Patienten mit Spondyloarthritis – Übersetzung ins Deutsche

Journal:Z Rheumatol. Year:2016; Volume:75Issue:(9):Pages:903-909.

Authors:Sieper J, Rudwaleit M, Lenaerts J, Wollenhaupt J, Myasoutova L, Park SH, Song YW, Yao R, Huyck S, Govoni M, Chitkara D, Vastesaeger N.

Title:Partial remission in ankylosing spondylitis and non-radiographic axial spondyloarthritis in treatment with infliximab plus naproxen or naproxen alone: associations between partial remission and baseline disease characteristics

Journal:Rheumatology (Oxford) Year:2016; Volume:55Issue:(11):Pages:1946-1953.

Authors:Rudwaleit M.

Title:Spondyloarthropathies: Identifying axial SpA in young adults with chronic back pain.

Journal:Nat Rev Rheumatol. Year:2016; Volume:12Issue:(7):Pages:378-380.

Authors:Poddubnyy D, Protopopov M, Haibel H, Braun J, Rudwaleit M, Sieper J.

Title:High disease activity according to the Ankylosing Spondylitis Disease Activity Score is associated with accelerated radiographic spinal progression in patients with early axial spondyloarthritis: results from the GErman SPondyloarthritis Inception Cohort

Journal:Ann Rheum Dis. Year:2016; Volume:75Issue:(12):Pages:2114-2118.

Authors:Bleil J, Maier R, Hempfing A, Sieper J, Appel H, Syrbe U.

Title:Granulation tissue eroding the subchondral bone also promotes new bone formation in ankylosing spondylitis

Journal:Arthritis Rheumatol. Year:2016; Volume:68Issue:(10):Pages:2456-2465.

Authors:Sieper J, Poddubnyy D.

Title:New evidence on the management of spondyloarthritis

Journal:Nat Rev Rheumatol. Year:2016; Volume:12Issue:(5):Pages:282-295.

Authors:Heldmann F, Baraliakos X, Kiltz U, Brandt J, van der Horst-Bruinsma IE, Landewé R, Sieper J, Burmester GR, van den Bosch F, de Vlam K, Gaston H, Gruenke M, Witt M, Appelboom T, Emery P, Dougados M, Leirisalo-Repo M, Breban M, Braun J.

Title:Clinical experience with the European Ankylosing Spondylitis Infliximab Cohort (EASIC): long-term extension over 7 years with focus on clinical efficacy and safety

Journal:Clin Exp Rheumatol Year:2016; Volume:34Issue:(2):Pages:184-90.

Authors:Poddubnyy D, Listing J, Sieper J.

Title:Course of active inflammatory and fatty lesions in patients with early axial spondyloarthritis treated with infliximab plus naproxen as compared to naproxen alone: Results from the INFAST study

Journal:Arthritis Rheumatol. Year:2016; Volume:68Issue:(8):Pages:1899-1903.

Authors:Braun J, Bessler F, Lakomek HJ, Rudwaleit M.

Title:Internationale Qualitätsindikatoren in der Rheumatologie. Vorschläge für die rheumatoide Arthritis

Journal:Z Rheumatol. Year:2016; Volume:75Issue:(3):Pages:330-337.

Authors:Sepriano A, Rudwaleit M, Sieper J, van den Berg R, Landewé R, van der Heijde D.

Title:Five-year follow-up of radiographic sacroiliitis: progression as well as improvement?

Journal:Ann Rheum Dis. Year:2016; Volume:75Issue:(6):Pages:1262-1263.

Authors:Sepriano A, Landewé R, van der Heijde D, Sieper J, Akkoc N, Brandt J, Braun J, Collantes-Estevez E, Dougados M, Fitzgerald O, Huang F, Gu J, Kirazli Y, Maksymowych WP, Marzo-Ortega H, Olivieri I, Ozgocmen S, Roussou E, Scarpato S, Sørensen IJ, Valle-Oñate R, Van den Bosch F, van der Horst-Bruinsma I, Weber U, Wei J, Rudwaleit M; ASAS.

Title:Predictive validity of the ASAS classification criteria for axial and peripheral spondyloarthritis after follow-up in the ASAS cohort: a final analysis

Journal:Ann Rheum Dis. Year:2016; Volume:75Issue:(6):Pages:1034-1042.

Authors:Althoff CE, Sieper J, Song IH, Weiß A, Diekhoff T, Haibel H, Hamm B, Hermann KG.

Title:Comparison of Clinical Examination versus Whole-body Magnetic Resonance Imaging of Enthesitis in Patients with Early Axial Spondyloarthritis during 3 Years of Continuous Etanercept Treatment

Journal:J Rheumatol. Year:2016; Volume:43Issue:(3):Pages:618-624.

Authors:Rudwaleit M, Rosenbaum JT, Landewé R, Marzo-Ortega H, Sieper J, van der Heijde D, Davies O, Bartz H, Hoepken B, Nurminen T, Deodhar A.

Title:Observed Incidence of Uveitis Following Certolizumab Pegol Treatment in Patients with Axial Spondyloarthritis

Journal:Arthritis Care Res (Hoboken). Year:2016; Volume:68Issue:(6):Pages:838-844.

Authors:Hammoudeh M, Abdulaziz S, Alosaimi H, Al-Rayes H, Aldeen Sarakbi H, Baamer M, Baraliakos X, Dahou Makhloufi C, Janoudi N, Shirazy K, Sieper J, Sukhbir U.

Title:Challenges of diagnosis and management of axial spondyloarthritis in North Africa and the Middle East: An expert consensus

Journal:J Int Med Res. Year:2016; Volume:44Issue:(2):Pages:216-230.

Authors:Atkinson SM, Bleil J, Maier R, Kühl AA, Thorn M, Serikawa K, Fox B, Kruse K, Haase C, Skov S, Nansen A, Syrbe U.

Title:Anti-RANKL treatment inhibits erosive joint destruction and lowers inflammation but has no effect on bone formation in the delayed-type hypersensitivity arthritis (DTHA) model

Journal:Arthritis Res Ther. Year:2016; Volume:18:Pages:28.

Authors:Rios Rodriguez V, Poddubnyy D.

Title:Golimumab for treatment of axial spondyloarthritis

Journal:Immunotherapy. Year:2016; Volume:8Issue:(2):Pages:107-115.

Authors:Rios Rodriguez V, Poddubnyy D.

Title:Etanercept for the treatment of non-radiographic axial spondyloarthritis

Journal:Expert Rev Clin Immunol. Year:2016; Volume:12Issue:(5):Pages:493-500.

Authors:Lambert RG, Bakker PA, van der Heijde D, Weber U, Rudwaleit M, Hermann KG, Sieper J, Baraliakos X, Bennett A, Braun J, Burgos-Vargas R, Dougados M, Pedersen SJ, Jurik AG, Maksymowych WP, Marzo-Ortega H, Østergaard M, Poddubnyy D, Reijnierse M, van den Bosch F, van der Horst-Bruinsma I, Landewé R.

Title:Defining active sacroiliitis on MRI for classification of axial spondyloarthritis: update by the ASAS MRI working group

Journal:Ann Rheum Dis. Year:2016; Volume:75Issue:(11):Pages:1958-1963.

Authors:Song IH, Brenneis C, Hammel L, Feldtkeller E, Listing J, Sieper J, Rudwaleit M.

Title:Ankylosing spondylitis self-help organisations - do members differ from non-members?

Journal:Joint Bone Spine. Year:2016; Volume:83Issue:(3):Pages:295-300.

Authors:Gossec L, Smolen JS, Ramiro S, de Wit M, Cutolo M, Dougados M, Emery P, Landewé R, Oliver S, Aletaha D, Betteridge N, Braun J, Burmester G, Cañete JD, Damjanov N, FitzGerald O, Haglund E, Helliwell P, Kvien TK, Lories R, Luger T, Maccarone M, Marzo-Ortega H, McGonagle D, McInnes IB, Olivieri I, Pavelka K, Schett G, Sieper J, van den Bosch F, Veale DJ, Wollenhaupt J, Zink A, van der Heijde D.

Title:European League Against Rheumatism (EULAR) recommendations for the management of psoriatic arthritis with pharmacological therapies: 2015 update

Journal:Ann Rheum Dis. Year:2016; Volume:75Issue:(3):Pages:499-510.

Authors:Rios Rodriguez V, Poddubnyy D.

Title:Old and new treatment targets in axial spondyloarthritis.

Journal:RMD Open. Year:2016; Volume:1Issue:(Suppl 1):Pages:e000054.

Authors:Song IH, Hermann KG, Haibel H, Althoff CE, Poddubnyy D, Listing J, Weiß A, Freundlich B, Lange E, Rudwaleit M, Sieper J.

Title:Inflammatory and fatty lesions in the spine and sacroiliac joints on whole-body MRI in early axial spondyloarthritis-3-Year data of the ESTHER trial

Journal:Semin Arthritis Rheum. Year:2016; Volume:45Issue:(4):Pages:404-410.

Authors:Pedersen SJ, Poddubnyy D, Sørensen IJ, Loft AG, Hindrup JS, Thamsborg G, Asmussen K, Hendricks O, Nørregaard J, Piil AD, Møller JM, Jurik AG, Balding L, Lambert RG, Sieper J, Østergaard M.

Title:Course of Magnetic Resonance Imaging-Detected Inflammation and Structural Lesions in the Sacroiliac Joints of Patients in the Randomized, Double-Blind, Placebo-Controlled Danish Multicenter Study of Adalimumab in Spondyloarthritis, as Assessed by...

Journal:Arthritis Rheumatol. Year:2016; Volume:68Issue:(2):Pages:418-429.

Authors:Baraliakos X, Borah B, Braun J, Baeten D, Laurent D, Sieper J, Emery P, McInnes IB, van Laar JM, Wordsworth P, Wollenhaupt J, Kellner H, Colin L, Vandenhende F, Radford K, Hueber W.

Title:Long-term effects of secukinumab on MRI findings in relation to clinical efficacy in subjects with active ankylosing spondylitis: an observational study

Journal:Ann Rheum Dis. Year:2016; Volume:75Issue:(2):Pages:408-412.

Authors:Baeten D, Sieper J, Braun J, Baraliakos X, Dougados M, Emery P, Deodhar A, Porter B, Martin R, Andersson M, Mpofu S, Richards HB; MEASURE 1 Study Group; MEASURE 2 Study Group.

Title:Secukinumab, an Interleukin-17A Inhibitor, in Ankylosing Spondylitis

Journal:N Engl J Med. Year:2015; Volume:373Issue:(26):Pages:2534-2548.

Authors:Appel H.

Title:Dr. Appel replies

Journal:J Rheumatol Year:2015; Volume:42Issue:(11):Pages:2211.

Authors:Poddubnyy D, van Tubergen A, Landewé R, Sieper J, van der Heijde D.

Title:Defining an optimal referral strategy for patients with a suspicion of axial spondyloarthritis: what is really important? Response to: 'Evaluating the ASAS recommendations for early referral of axial spondyloarthritis in patients with chronic low back pai

Journal:Ann Rheum Dis. Year:2015; Volume:74Issue:(12):Pages:e69.

Authors:Maksymowych WP, Dougados M, van der Heijde D, Sieper J, Braun J, Citera G, Van den Bosch F, Logeart I, Wajdula J, Jones H, Marshall L, Bonin R, Pedersen R, Vlahos B, Kotak S, Bukowski JF.

Title:Clinical and MRI responses to etanercept in early non-radiographic axial spondyloarthritis: 48-week results from the EMBARK study

Journal:Ann Rheum Dis. Year:2015; Volume:75Issue:(7):Pages:1328-1335.

Authors:Sieper J, Listing J, Poddubnyy D, Song IH, Hermann KG, Callhoff J, Syrbe U, Braun J, Rudwaleit M.

Title:Effect of continuous versus on-demand treatment of ankylosing spondylitis with diclofenac over 2 years on radiographic progression of the spine: results from a randomised multicentre trial (ENRADAS)

Journal:Ann Rheum Dis. Year:2015; Volume:75Issue:(8):Pages:1438-1443.

Authors:Conrad K, Wu P, Sieper J, Syrbe U.

Title:In vivo pre-activation of monocytes in patients with axial spondyloarthritis

Journal:Arthritis Res Ther. Year:2015; Volume:16Issue:(17):Pages:179.

Authors:Sieper J, van der Heijde D, Dougados M, Maksymowych WP, Scott BB, Boice JA, Berd Y, Bergman G, Curtis S, Tzontcheva A, Huyck S, Weng HH.

Title:A randomized, double-blind, placebo-controlled, sixteen-week study of subcutaneous golimumab in patients with active nonradiographic axial spondyloarthritis.

Journal:Ann Rheum Dis. Year:2015; Volume:67Issue:(10):Pages:2702-2712.

Authors:Bleil J, Sieper J, Maier R, Schlichting U, Hempfing A, Syrbe U, Appel H.

Title:Cartilage in facet joints of patients with ankylosing spondylitis (AS) shows signs of cartilage degeneration rather than chondrocyte hypertrophy: implications for joint remodeling in AS.

Journal:Arthritis Res Ther. Year:2015; Volume:17Issue:(17):Pages:170.

Authors:Mease P, Sieper J, Van den Bosch F, Rahman P, Pangan A.

Title:Reply: To PMID 25545240

Journal:Arthritis Rheumatol. Year:2015; Volume:67Issue:(10):Pages:2793-2794.

Authors:Poddubnyy D, Haibel H, Braun J, Rudwaleit M, Sieper J.

Title:Brief Report: Clinical Course Over Two Years in Patients With Early Nonradiographic Axial Spondyloarthritis and Patients With Ankylosing Spondylitis Not Treated With Tumor Necrosis Factor Blockers: Results From the German Spondyloarthritis Inception Cohor

Journal:Arthritis Rheumatol. Year:2015; Volume:67Issue:(9):Pages:2369-2375.

Authors:Poddubnyy D, van Tubergen A, Landewé R, Sieper J, van der Heijde D; Assessment of SpondyloArthritis international Society (ASAS).

Title:Development of an ASAS-endorsed recommendation for the early referral of patients with a suspicion of axial spondyloarthritis

Journal:Ann Rheum Dis. Year:2015; Volume:74Issue:(8):Pages:1483-1487.

Authors:Bleil J, Maier R, Syrbe U, Sieper J, Appel H.

Title:In situ analysis of interleukin-6 expression at different sites of zygapophyseal joints from patients with ankylosing spondylitis in comparison to controls.

Journal:Scand J Rheumatol. Year:2015; Volume:44Issue:(4):Pages:296-301.

Authors:Haibel H, Sieper J.

Title:Enthesitis im Rahmen von Spondyloarthritiden

Journal:Orthopade. Year:2015; Volume:44Issue:(5):Pages:395-404.

Authors:Mandl P, Navarro-Compán V, Terslev L, Aegerter P, van der Heijde D, D'Agostino MA, Baraliakos X, Pedersen SJ, Jurik AG, Naredo E, Schueller-Weidekamm C, Weber U, Wick MC, Bakker PA, Filippucci E, Conaghan PG, Rudwaleit M, Schett G, Sieper J, Tarp S, Marzo-Ortega H, Østergaard M; European League Against Rheumatism (EULAR).

Title:EULAR recommendations for the use of imaging in the diagnosis and management of spondyloarthritis in clinical practice

Journal:Ann Rheum Dis. Year:2015; Volume:74Issue:(7):Pages:1327-1339.

Authors:Appel H, Sieper J.

Title:Analysis of bone samples from patients with spondyloarthritides-identifying causes of new bone formation in axial spondyloarthritis.

Journal:J Rheumatol. Year:2015; Volume:42Issue:(4):Pages:561-563.

Authors:Sieper J, Kivitz A, van Tubergen A, Deodhar A, Coteur G, Woltering F, Landewé R.

Title:Impact of Certolizumab Pegol on Patient-Reported Outcomes in Patients With Axial Spondyloarthritis

Journal:Arthritis Care Res (Hoboken). Year:2015; Volume:67Issue:(10):Pages:1475-1480.

Authors:Sieper J, Braun J.

Title:Erfahrungen aus 15 Jahren Investigator-initiierten klinischen Studien zur axialen Spondyloarthritis

Journal:Z Rheumatol. Year:2015; Volume:74Issue:(2):Pages:125-131.

Authors:Sieper J, Braun J.

Title:Von der Ungewissheit zur Evidenz

Journal:Z Rheumatol. Year:2015; Volume:74Issue:(2):Pages:104-105.

Authors:Haibel H, Sieper J.

Title:Enthesitis im Rahmen von Spondyloarthritiden

Journal:Z Rheumatol. Year:2015; Volume:74Issue:(1):Pages:39-48.

Authors:Mease P, Sieper J, Van den Bosch F, Rahman P, Karunaratne PM, Pangan AL.

Title:Randomized controlled trial of adalimumab in patients with nonpsoriatic peripheral spondyloarthritis

Journal:Arthritis Rheumatol. Year:2015; Volume:67Issue:(4):Pages:914-923.

Authors:van der Heijde D, Breban M, Halter D, DiVittorio G, Bratt J, Cantini F, Kary S, Pangan AL, Kupper H, Rathmann SS, Sieper J, Mease PJ.

Title:Maintenance of improvement in spinal mobility, physical function and quality of life in patients with ankylosing spondylitis after 5 years in a clinical trial of adalimumab

Journal:Rheumatology (Oxford). Year:2015; Volume:54Issue:(7):Pages:1210-1219.

Authors:Boonen A, Sieper J, van der Heijde D, Dougados M, Bukowski JF, Valluri S, Vlahos B, Kotak S.

Title:The burden of non-radiographic axial spondyloarthritis.

Journal:Semin Arthritis Rheum. Year:2015; Volume:44Issue:(5):Pages:556-562.

Authors:Poddubnyy D, Gensler LS.

Title:Spontaneous, drug-induced, and drug-free remission in peripheral and axial spondyloarthritis.

Journal:Best Pract Res Clin Rheumatol. Year:2015; Volume:28Issue:(5):Pages:807-818.

Authors:Haftmann C, Stittrich AB, Zimmermann J, Fang Z, Hradilkova K, Bardua M, Westendorf K, Heinz GA, Riedel R, Siede J, Lehmann K, Weinberger EE, Zimmel D, Lauer U, Häupl T, Sieper J, Backhaus M, Neumann C, Hoffmann U, Porstner M, Chen W, Grün JR, Baumgrass R, Matz M, Löhning M, Scheffold A, Wittmann J, Chang HD, Rajewsky N, Jäck HM, Radbruch A, Mashreghi MF.

Title:miR-148a is upregulated by Twist1 and T-bet and promotes Th1-cell survival by regulating the proapoptotic gene Bim.

Journal:Eur J Immunol. Year:2015; Volume:45Issue:(4):Pages:1192-1205.

Authors:Sieper J, Landewé R, Rudwaleit M, van der Heijde D, Dougados M, Mease PJ, Braun J, Deodhar A, Kivitz A, Walsh J, Hoepken B, Nurminen T, Maksymowych WP.

Title:Effect of certolizumab pegol over ninety-six weeks in patients with axial spondyloarthritis: results from a phase III randomized trial

Journal:Arthritis Rheumatol. Year:2015; Volume:67Issue:(3):Pages:668-677.

Authors:Deodhar A, Sieper J, Reveille JD, van der Heijde D, Gensler LS, Landewé R; Spondyloarthritis Research and Treatment Network and Assessment of SpondyloArthritis international Society authors.

Title:Reply: To PMID 25154344

Journal:Arthritis Rheumatol. Year:2015; Volume:67Issue:(3):Pages:856-857.

Authors:Syrbe U, Callhoff J, Conrad K, Poddubnyy D, Haibel H, Junker S, Frommer KW, Müller-Ladner U, Neumann E, Sieper J.

Title:Serum adipokine levels in patients with ankylosing spondylitis and their relationship to clinical parameters and radiographic spinal progression

Journal:Arthritis Rheumatol. Year:2015; Volume:67Issue:(3):Pages:678-685.

Authors:Braun J, Baraliakos X, Kiltz U, Heldmann F, Sieper J.

Title:Classification and diagnosis of axial spondyloarthritis--what is the clinically relevant difference?

Journal:J Rheumatol. Year:2015; Volume:42Issue:(1):Pages:31-38.

Authors:Syrbe U, Siegmund B.

Title:Bone marrow Th17 TNFα cells induce osteoclast differentiation and link bone destruction to IBD

Journal:Gut. Year:2015; Volume:64Issue:(7):Pages:1011-1012.

Authors:Song IH, Hermann KG, Haibel H, Althoff CE, Poddubnyy D, Listing J, Weiß A, Lange E, Freundlich B, Rudwaleit M, Sieper J.

Title:Prevention of new osteitis on magnetic resonance imaging in patients with early axial spondyloarthritis during 3 years of continuous treatment with etanercept: data of the ESTHER trial

Journal:Rheumatology (Oxford). Year:2015; Volume:54Issue:(2):Pages:257-261.

Authors:Callhoff J, Sieper J, Weiß A, Zink A, Listing J.

Title:Efficacy of TNFα blockers in patients with ankylosing spondylitis and non-radiographic axial spondyloarthritis: a meta-analysis

Journal:Ann Rheum Dis. Year:2015; Volume:74Issue:(6):Pages:1241-1248.

Authors:Sieper J, Braun J, Kay J, Badalamenti S, Radin AR, Jiao L, Fiore S, Momtahen T, Yancopoulos GD, Stahl N, Inman RD.

Title:Sarilumab for the treatment of ankylosing spondylitis: results of a Phase II, randomised, double-blind, placebo-controlled study (ALIGN)

Journal:Ann Rheum Dis. Year:2015; Volume:74Issue:(6):Pages:1051-1057.

Authors:Moltó A, Paternotte S, van der Heijde D, Claudepierre P, Rudwaleit M, Dougados M.

Title:Evaluation of the validity of the different arms of the ASAS set of criteria for axial spondyloarthritis and description of the different imaging abnormalities suggestive of spondyloarthritis: data from the DESIR cohort

Journal:Ann Rheum Dis. Year:2015; Volume:74Issue:(4):Pages:746-751.

Authors:van der Heijde D, Sieper J, Elewaut D, Deodhar A, Pangan AL, Dorr AP.

Title:Referral patterns, diagnosis, and disease management of patients with axial spondyloarthritis: results of an international survey

Journal:J Clin Rheumatol. Year:2014; Volume:20Issue:(8):Pages:411-417.

Authors:Feldtkeller E, Rudwaleit M.

Title:Comment on 'Diagnostic delay in patients with rheumatoid arthritis, psoriatic arthritis and ankylosing spondylitis: results from the Danish nationwide DANBIO registry'

Journal:J Clin Rheumatol. Year:2014; Volume:73Issue:(12):Pages:e77.

Authors:Kiltz U, Sieper J, Kellner H, Krause D, Rudwaleit M, Chenot JF, Stallmach A, Jaresch S, Braun J; German Society for Rheumatology.

Title:DGRh-S3-Leitlinie Axiale Spondyloarthritis inklusive Morbus Bechterew und Frühformen. DGRh-S3-Leitlinie Axiale Spondyloarthritis inklusive Morbus Bechterew und Frühformen: 8.4 Medikamentöse Therapie, 8.5 Evaluation des Therapieerfolgs medikamentöser..

Journal:Z Rheumatol. Year:2014; Volume:73Issue:(Suppl 2):Pages:78-96.

Authors:Kiltz U, Sieper J, Rudwaleit M, Kellner H, Krause D, Böhle E, Böhm H, Böhncke WH, Chenot JF, Heiligenhaus A, Jaresch S, Mau W, Oberschelp U, Pleyer U, Repschläger U, Schneider E, Smolenski U, Stallmach A, Stemmer M, Swoboda B, Ulrich C, Winking M, Braun J; German Society for Rheumatology.

Title:DGRh-S3-Leitlinie Axiale Spondyloarthritis inklusive Morbus Bechterew und Frühformen: 8 Therapie, 8.1 Behandlungskonzept, 8.2 Therapieziele und -strategie

Journal:Z Rheumatol. Year:2014; Volume:73Issue:(Suppl 2):Pages:69-70.

Authors:Kiltz U, Rudwaleit M, Sieper J, Krause D, Oberschelp U, Schneider E, Swoboda B, Böhm H, Braun J; German Society for Rheumatology.

Title:DGRh-S3-Leitlinie Axiale Spondyloarthritis inklusive Morbus Bechterew und Frühformen: 7 Krankheitsaktivität und Prognose der SpA

Journal:Z Rheumatol. Year:2014; Volume:73Issue:(Suppl 2):Pages:66-68.

Authors:Kiltz U, Rudwaleit M, Sieper J, Krause D, Hermann KG, Braun J; German Society for Rheumatology.

Title:DGRh-S3-Leitlinie Axiale Spondyloarthritis inklusive Morbus Bechterew und Frühformen: 6 Diagnostik

Journal:Z Rheumatol. Year:2014; Volume:73Issue:(Suppl 2):Pages:49-65.

Authors:Kiltz U, Rudwaleit M, Sieper J, Krause D, Heiligenhaus A, Pleyer U, Chenot JF, Stallmach A, Jaresch S, Oberschelp U, Schneider E, Swoboda B, Böhm H, Hermann KG, Böhncke WH, Braun J; German Society for Rheumatology.

Title:DGRh-S3-Leitlinie Axiale Spondyloarthritis inklusive Morbus Bechterew und Frühformen: 5 Erstdiagnose/Überweisungsstrategie

Journal:Z Rheumatol. Year:2014; Volume:73Issue:(Suppl 2):Pages:44-48.

Authors:Kiltz U, Rudwaleit M, Sieper J, Braun J; German Society for Rheumatology.

Title:DGRh-S3-Leitlinie Axiale Spondyloarthritis inklusive Morbus Bechterew und Frühformen: 4 Klassifikations- und Diagnosekriterien

Journal:Z Rheumatol. Year:2014; Volume:73Issue:(Suppl 2):Pages:40-43.

Authors:Kiltz U, Rudwaleit M, Sieper J, Krause D, Chenot JF, Stallmach A, Jaresch S, Oberschelp U, Schneider E, Swoboda B, Böhm H, Heiligenhaus A, Pleyer U, Böhncke WH, Stemmer M, Braun J; German Society for Rheumatology.

Title:DGRh-S3-Leitlinie Axiale Spondyloarthritis inklusive Morbus Bechterew und Frühformen: 3 Klinische Symptomatik

Journal:Z Rheumatol. Year:2014; Volume:73Issue:(Suppl 2):Pages:28-39.

Authors:Kiltz U, Sieper J, Rudwaleit M, Kellner H, Krause D, Böhle E, Böhm H, Böhncke WH, Chenot JF, Heiligenhaus A, Hermann KG, Jaresch S, Mau W, Oberschelp U, Pleyer U, Repschläger U, Schneider E, Smolenski U, Stallmach A, Stemmer M, Swoboda B, Ulrich C, Winking M, Braun J; German Society for Rheumatology.

Title:DGRh-S3-Leitlinie Axiale Spondyloarthritis inklusive Morbus Bechterew und Frühformen: 2 Präambel

Journal:Z Rheumatol. Year:2014; Volume:73Issue:(Suppl 2):Pages:26-27.

Authors:Kiltz U, Sieper J, Rudwaleit M, Kellner H, Krause D, Böhle E, Böhm H, Böhncke WH, Chenot JF, Heiligenhaus A, Hermann KG, Jaresch S, Mau W, Oberschelp U, Pleyer U, Repschläger U, Schneider E, Smolenski U, Stallmach A, Stemmer M, Swoboda B, Ulrich C, Winking M, Braun J; German Society for Rheumatology.

Title:DGRh-S3-Leitlinie Axiale Spondyloarthritis inklusive Morbus Bechterew und Frühformen: 1 Einleitung/Vorbemerkung

Journal:Z Rheumatol. Year:2014; Volume:73Issue:(Suppl 2):Pages:23-25.

Authors:Deodhar A, Reveille JD, van den Bosch F, Braun J, Burgos-Vargas R, Caplan L, Clegg DO, Colbert RA, Gensler LS, van der Heijde D, van der Horst-Bruinsma IE, Inman RD, Maksymowych WP, Mease PJ, Raychaudhuri S, Reimold A, Rudwaleit M, Sieper J, Weisman MH, Landewé RB.

Title:The concept of axial spondyloarthritis: joint statement of the spondyloarthritis research and treatment network and the Assessment of SpondyloArthritis international Society in response to the US Food and Drug Administration's comments and concerns

Journal:Arthritis Rheumatol. Year:2014; Volume:66Issue:(10):Pages:2649-56.

Authors:Song IH, Hermann KG, Haibel H, Althoff CE, Poddubnyy D, Listing J, Weiß A, Buß B, Freundlich B, Lange E, Alten R, Rudwaleit M, Sieper J.

Title:Consistently Good clinical response in patients with early axial spondyloarthritis after 3 years of continuous treatment with etanercept: longterm data of the ESTHER trial

Journal:J Rheumatol. Year:2014; Volume:41Issue:(10):Pages:2034-2040.

Authors:Pink M, Ratsch BA, Mardahl M, Schröter MF, Engelbert D, Triebus J, Hamann A, Syrbe U.

Title:Identification of two regulatory elements controlling Fucosyltransferase 7 transcription in murine CD4+ T cells

Journal:Mol Immunol. Year:2014; Volume:62Issue:(1):Pages:1-9.

Authors:Dougados M, van der Heijde D, Sieper J, Braun J, Maksymowych WP, Citera G, Miceli-Richard C, Wei JC, Pedersen R, Bonin R, Rahman MU, Logeart I, Wajdula J, Koenig AS, Vlahos B, Alvarez D, Bukowski JF.

Title:Symptomatic efficacy of etanercept and its effects on objective signs of inflammation in early nonradiographic axial spondyloarthritis: a multicenter, randomized, double-blind, placebo-controlled trial

Journal:Arthritis Rheumatol. Year:2014; Volume:66Issue:(8):Pages:2091-2102.

Authors:Turina MC, Sieper J, Yeremenko N, Conrad K, Haibel H, Rudwaleit M, Baeten D, Poddubnyy D.

Title:Calprotectin serum level is an independent marker for radiographic spinal progression in axial spondyloarthritis

Journal:Ann Rheum Dis. Year:2014; Volume:73Issue:(9):Pages:1746-1748.

Authors:Sieper J, Poddubnyy D.

Title:Inflammation, new bone formation and treatment options in axial spondyloarthritis

Journal:Ann Rheum Dis. Year:2014; Volume:73Issue:(8):Pages:1439-1441.

Authors:Poddubnyy D, Sieper J.

Title:Similarities and differences between nonradiographic and radiographic axial spondyloarthritis: a clinical, epidemiological and therapeutic assessment

Journal:Curr Opin Rheumatol. Year:2014; Volume:26Issue:(4):Pages:377-383.

Authors:Becker H, Appel H, Fassbinder T, Heitzmann D, Willeke P, Jacobi AM.

Title:Rituximab zur Therapie des Felty-Syndroms

Journal:Z Rheumatol. Year:2014; Volume:73Issue:(5):Pages:465-466.

Authors:Bleil J, Maier R, Hempfing A, Schlichting U, Appel H, Sieper J, Syrbe U.

Title:Histomorphologic and histomorphometric characteristics of zygapophyseal joint remodeling in ankylosing spondylitis

Journal:Arthritis Rheumatol. Year:2014; Volume:66Issue:(7):Pages:1745-1754.

Authors:van der Heijde D, Sieper J, Maksymowych WP, Brown MA, Lambert RG, Rathmann SS, Pangan AL.

Title:Spinal inflammation in the absence of sacroiliac joint inflammation on magnetic resonance imaging in patients with active nonradiographic axial spondyloarthritis

Journal:Arthritis Rheumatol. Year:2014; Volume:66Issue:(3):Pages:667-673.

Authors:Krohn M, Braum LS, Sieper J, Song IH, Weiss A, Callhoff J, Althoff CE, Hamm B, Hermann KG.

Title:Erosions and fatty lesions of sacroiliac joints in patients with axial spondyloarthritis: evaluation of different MRI techniques and two scoring methods

Journal:J Rheumatol. Year:2014; Volume:41Issue:(3):Pages:473-480.

Authors:Weiß A, Song IH, Haibel H, Listing J, Sieper J.

Title:Good correlation between changes in objective and subjective signs of inflammation in patients with short- but not long duration of axial spondyloarthritis treated with tumor necrosis factor-blockers

Journal:Arthritis Res Ther. Year:2014; Volume:16Issue:(1):Pages:R30.

Authors:Sieper J.

Title:Response to H Zeidler's comments on the INFAST study

Journal:Ann Rheum Dis. Year:2014; Volume:73Issue:(4):Pages:e19.

Authors:Poddubnyy D, Hermann KG, Callhoff J, Listing J, Sieper J.

Title:Ustekinumab for the treatment of patients with active ankylosing spondylitis: results of a 28-week, prospective, open-label, proof-of-concept study (TOPAS)

Journal:Ann Rheum Dis. Year:2014; Volume:73Issue:(5):Pages:817-823.

Authors:Landewé R, Braun J, Deodhar A, Dougados M, Maksymowych WP, Mease PJ, Reveille JD, Rudwaleit M, van der Heijde D, Stach C, Hoepken B, Fichtner A, Coteur G, de Longueville M, Sieper J.

Title:Efficacy of certolizumab pegol on signs and symptoms of axial spondyloarthritis including ankylosing spondylitis: 24-week results of a double-blind randomised placebo-controlled Phase 3 study

Journal:Ann Rheum Dis. Year:2014; Volume:73Issue:(1):Pages:39-47.

Authors:Poddubnyy D, Conrad K, Haibel H, Syrbe U, Appel H, Braun J, Rudwaleit M, Sieper J.

Title:Elevated serum level of the vascular endothelial growth factor predicts radiographic spinal progression in patients with axial spondyloarthritis

Journal:Ann Rheum Dis. Year:2014; Volume:73Issue:(12):Pages:2137-2143.

Authors:Baraliakos X, Heldmann F, Callhoff J, Listing J, Appelboom T, Brandt J, Van den Bosch F, Breban M, Burmester G, Dougados M, Emery P, Gaston H, Grunke M, Van Der Horst-Bruinsma IE, Landewé R, Leirisalo-Repo M, Sieper J, De Vlam K, Pappas D, Kiltz U, Van Der Heijde D, Braun J.

Title:Which spinal lesions are associated with new bone formation in patients with ankylosing spondylitis treated with anti-TNF agents? A long-term observational study using MRI and conventional radiography

Journal:Ann Rheum Dis. Year:2014; Volume:73Issue:(10):Pages:1819-1825.

Authors:Sieper J, Porter-Brown B, Thompson L, Harari O, Dougados M.

Title:Assessment of short-term symptomatic efficacy of tocilizumab in ankylosing spondylitis: results of randomised, placebo-controlled trials

Journal:Ann Rheum Dis. Year:2014; Volume:73Issue:(1):Pages:95-100.

Authors:Smolen JS, Braun J, Dougados M, Emery P, Fitzgerald O, Helliwell P, Kavanaugh A, Kvien TK, Landewé R, Luger T, Mease P, Olivieri I, Reveille J, Ritchlin C, Rudwaleit M, Schoels M, Sieper J, Wit Md, Baraliakos X, Betteridge N, Burgos-Vargas R, Collantes-Estevez E, Deodhar A, Elewaut D, Gossec L, Jongkees M, Maccarone M, Redlich K, van den Bosch F, Wei JC, Winthrop K, van der Heijde D.

Title:Treating spondyloarthritis, including ankylosing spondylitis and psoriatic arthritis, to target: recommendations of an international task force.

Journal:Ann Rheum Dis. Year:2014; Volume:73Issue:(1):Pages:6-16.

Authors:Schoels MM, Braun J, Dougados M, Emery P, Fitzgerald O, Kavanaugh A, Kvien TK, Landewé R, Luger T, Mease P, Olivieri I, Reveille J, Ritchlin C, Rudwaleit M, Sieper J, Smolen JS, Wit Md, van der Heijde D.

Title:Treating axial and peripheral spondyloarthritis, including psoriatic arthritis, to target: results of a systematic literature search to support an international treat-to-target recommendation in spondyloarthritis.

Journal:Ann Rheum Dis. Year:2014; Volume:73Issue:(1):Pages:238-242.

Authors:Sieper J, Lenaerts J, Wollenhaupt J, Rudwaleit M, Mazurov VI, Myasoutova L, Park S, Song Y, Yao R, Chitkara D, Vastesaeger N; All INFAST Investigators.

Title:Maintenance of biologic-free remission with naproxen or no treatment in patients with early, active axial spondyloarthritis: results from a 6-month, randomised, open-label follow-up study, INFAST Part 2

Journal:Ann Rheum Dis. Year:2014; Volume:73Issue:(1):Pages:108-113.

Authors:Sieper J, Lenaerts J, Wollenhaupt J, Rudwaleit M, Mazurov VI, Myasoutova L, Park S, Song Y, Yao R, Chitkara D, Vastesaeger N; All INFAST Investigators.

Title:Efficacy and safety of infliximab plus naproxen versus naproxen alone in patients with early, active axial spondyloarthritis: results from the double-blind, placebo-controlled INFAST study, Part 1

Journal:Ann Rheum Dis. Year:2014; Volume:73Issue:(1):Pages:101-107.

Authors:Baerlecken NT, Nothdorft S, Stummvoll GH, Sieper J, Rudwaleit M, Reuter S, Matthias T, Schmidt RE, Witte T.

Title:Autoantibodies against CD74 in spondyloarthritis

Journal:Ann Rheum Dis. Year:2014; Volume:73Issue:(6):Pages:1211-1214.

Authors:Haibel H, Fendler C, Listing J, Callhoff J, Braun J, Sieper J.

Title:Efficacy of oral prednisolone in active ankylosing spondylitis: results of a double-blind, randomised, placebo-controlled short-term trial

Journal:Ann Rheum Dis. Year:2014; Volume:73Issue:(1):Pages:243-246.

Authors:Baraliakos X, Haibel H, Listing J, Sieper J, Braun J.

Title:Continuous long-term anti-TNF therapy does not lead to an increase in the rate of new bone formation over 8 years in patients with ankylosing spondylitis.

Journal:Ann Rheum Dis. Year:2014; Volume:73Issue:(4):Pages:710-715.

Authors:McInnes IB, Sieper J, Braun J, Emery P, van der Heijde D, Isaacs JD, Dahmen G, Wollenhaupt J, Schulze-Koops H, Kogan J, Ma S, Schumacher MM, Bertolino AP, Hueber W, Tak PP.

Title:Efficacy and safety of secukinumab, a fully human anti-interleukin-17A monoclonal antibody, in patients with moderate-to-severe psoriatic arthritis: a 24-week, randomised, double-blind, placebo-controlled, phase II proof-of-concept trial

Journal:Ann Rheum Dis. Year:2014; Volume:73Issue:(2):Pages:349-356.